Characterized for the first time in zoo mammals pulmonary arterial disease due to high-altitude hypertension and complicated with right-sided cardiac hypertrophy and heart failure. This disease is similar to the subacute and chronic mountain sickness in humans and brisket disease of cattle living at high altitudes. A fascinating study based on a systematic necropsy work with emphasis on gross cardiac pathology and histopathology of arteries in the lungs initiated at Africam Safari while Carles Juan-Sallés was staff pathologist at this widely-recognized zoological park in Puebla (México), which can be of particular interest for the numerous zoological gardens in Latin America located at altitudes above 2,000 m - Juan-Sallés C, et al: Pulmonary arterial disease associated with right-sided cardiac hypertrophy and congestive heart failure in zoo mammals housed at 2,100 m above sea level. Journal of Zoo and Wildlife Diseases 46:825-32, 2015